December 2024 - Prodia The CRO

SpaceSlots Casino Review 2025 Cosmic Bonuses & 100 Free Spins Offer

Posted on December 13, 2024 by admin

SpaceSlots Casino brings together several features that make it worth trying. The user interface stands out — colours are bright, sections are easy to read, and menus are simple to use on all devices. One of the strongest parts is the Challenges system, where players can complete tasks and exchange loyalty points in the Shop or unlock spins on the Lucky Wheel. Live roulette games are one of the most active parts of the live section. Players can place bets on numbers, colours, or groups, then watch the wheel spin live. Some rooms include VIP tables, while others keep to classic layouts.

Is there a Space Casino cashback bonus?

While SpaceSlots Casino doesn’t have a dedicated poker section, there are still plenty of exciting games available. These include Omaha Poker, Pai Gow Poker, Texas Hold’em Bonus, and many others, all featuring live dealer streaming. Each one accepts players without a UKGC licence and supports quick sign-up.

The Lucky Wheel Feature

Space Casino has a UK Gambling Commission licence, which means it’s safe and legal for UK players. The licence ensures the site treats users fairly and also means its games have been verified as fair to play. If you need assistance while playing at Space Casino, there’s a chat icon at the bottom of every page. Opening this will let you instantly connect to a helpful member of the support team, but you can also get fast answers from the FAQ page.

Table Games

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Finally, a feature called Apex can increase your multiplier by up to 20 times.
Tasks can be locked at first and open when a player reaches a higher level.
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Space Slots is largely popular in the online casino space, considering it recently launched. However, it is working hard towards establishing itself as a decent brand. With over 3,000 games, a modern appeal, and a range of crypto and fiat payments, players globally will find the platform good enough. This category includes not only classic card and table games, such as online blackjack, roulette, and Sic Bo, but also popular game show titles like Monopoly Live and Mega Ball.
This time, the game was released by Games Global to leverage wider distribution channels, and this slot utilizes the company’s well-known Link&Win gameplay mechanic. Yes, Bitcoin is accepted for both deposits and withdrawals, making it a good choice for players who prefer crypto payments. This review covers everything you need to know about the casino — how to sign up, deposit, withdraw, and use all the available features. You’ll also learn about its pros and cons and how to claim a 400% bonus up to £2000 + 100 free spins on your first deposit. Over 50 table games include Blackjack Classic (RTP ~99.5%), French Roulette (RTP ~97.3%), Baccarat, and Oasis Poker Classic, catering to both beginners and seasoned players. SpaceSlots website casino appears very structured at first glance, and the filter function allows you to search for your favorite game.
With a great variety of games and a lucrative, fuss-free offer, this casino is establishing itself as a player-favourite, and for good reason. If you’re shopping for a new online casino that’s tailored for everyone, consider giving Mega Riches a spin. Gamblers enjoy playing space slots because these games typically have engaging space visuals that improve the whole experience of playing. In addition to this, they provide fantastic payouts and a plethora of extras. Space-themed slot machine CritterPop by AvatarUX features 6 reels, 65,346 paylines, and a return-to-player percentage of 96.08%.
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Space Casino Mobile Gaming

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The game’s major attraction would be Starburst Wild—a multicolored rainbow icon that might show up on reels 2, 3, or 4. Upon landing, it fills the entire reel, locks in place, and initiates a respin. If another expanding Starburst Wild appears during the respin, both expanding wilds will stay in place for a third consecutive respin. Cowboys, train robberies, sheriffs versus bandits, you know the drill.

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Brace yourself for dazzling graphics, out-of-this-world soundtracks, and stellar bonus rounds on the best space themed online slots.
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After the first one, the Lucky Wheel becomes active and adds a fun bonus spin feature.

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Played on a 5×3 grid with 25 paylines, Fluffy in Space is an easy slot to play and offers a fun gaming experience. One of the advantages is the above average RTP of 96.35% as well as the free spins round which is triggered when you land three or more planet scatter symbols. Features are the first thing that players look for on the hunt for a top slot. The very best space themed slots are armed with the biggest and most valuable features. For players who are captivated by the idea of space exploration, these slots offer a chance to indulge in their curiosity and experience the thrill of the unknown. Special features also play a part in making space slots attractive.
However, with the lack of ongoing promotions and a steep 50x wagering requirement, is Space Slots Casino worth a shot? New players at SpaceSlots Casino can claim a rewarding welcome package spread across their first five deposits. With up to €/£/$6,000 in bonus credit and 175 free spins, this offer ensures plenty of excitement for newcomers. A minimum deposit of €/£/$20 is required for each bonus, and all five deposits must be made to unlock the full offer. Aliens aplenty in this fun space game from the kings of the online slots world, NetEnt.

When free spins are active, each bonus symbol you land on awards an additional spin. Starburst is a slot game developed by NetEnt, featuring 5 reels, 10 paylines, a maximum payout of 500 times the wager per spin, and an RTP of 96%. Slot machines that are centered on the concept of space are referred to as space slots. These typically incorporate various space-related symbols, such as extraterrestrial beings, planets, galaxies, spaceships, astronauts, explorers, space missions, and so on. Vibrant visuals and engaging storylines open up a completely different world – that of Asian-themed slot games.

Methadone Withdrawal Schedule: Timelines & More Delphi

Posted on December 12, 2024 by admin

Read on to learn more about the complexities of methadone addiction, the challenges of withdrawal, and the vital importance of seeking professional help to navigate this treacherous path to recovery. Withdrawal is extremely uncomfortable, and the risk of returning to other opiates is high. For this reason, some people discuss staying on methadone treatment at lower doses if they can. Once a person is stable at a lower dose, the doctor will attempt to taper you from the drug again. Each person will experience withdrawal differently, based on the amount they were taking and other factors. For that reason, you must speak with your doctor about what to expect.

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take methadone while breastfeeding. Methadone is available as many different products that are taken in different ways.

Recovery Support

You and your care team will work together to determine how long you will need to take this medication. If your care team wants you to stop this medication, the dose will be slowly lowered over time to reduce the risk of side effects. Taking this medication with other substances that cause drowsiness, such as alcohol, benzodiazepines, or other opioids can cause serious side effects. Call emergency services if you have problems breathing or staying awake. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs.

Establish an appropriate drug testing program with policies to prevent falsification of specimens and to respond to tests that are negative for methadone. May have lower levels of opioid tolerance based on their recent history. Assess recent opioid use, including frequency, quantity, type, route, and recency (last day of use and use in the past 30 days). Caution patients that methadone may affect cognition and psychomotor performance and can have sedating effects. Urge patients to be cautious in using heavy machinery and driving until they are sure that their abilities are not compromised.

Warnings for people with certain health conditions

Abrupt cessation of this long-acting opioid can lead to severe methadone withdrawal symptoms, significantly increasing the risk of relapse due to the discomfort these symptoms cause.
If withdrawal symptoms lessen, the patient should return the next day to be reassessed and to continue the dose induction process.
It is important for people to be aware of the possible risks of opioid use during pregnancy, as well as treatment options including medications for opioid use disorder.
Your doctor may change your dose of methadone during your treatment.
If you take methadone for opioid use disorder, you will get your medicine from your treatment program.

If you experience pain during your treatment, your doctor may increase your dose or may prescribe an additional medication to control your pain. Talk to your doctor about how you are feeling during your treatment with methadone. If you feel that your pain is not controlled or if your pain increases, becomes worse, or if you have new pain or an increased sensitivity to pain while you are taking methadone, call your doctor. Do not take extra doses of methadone or take doses of methadone earlier than they are scheduled even if you experience pain. If you have what helps with methadone withdrawal an addiction to another opioid, your doctor may give you methadone to prevent you from having severe withdrawal symptoms.

Outpatient treatment is also an option for those whose methadone addictions have been diagnosed as minor by a substance abuse professional.
Peak withdrawal occurs within three to eight days after last use.
Medical clinics dispensing methadone should maintain clear records of the amount of methadone dispensed each day, and the amount of methadone stored on the premises.
If you continue to experience pain after you finish taking methadone, call your doctor.
Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Questions about treatment?

Outpatient treatment is also generally recommended for those who have completed an inpatient program but are still new to sobriety. Most medical detoxes provide a tapering off of the drug, or reducing the user’s dosage over a period of weeks. This method reduces the severity of withdrawal symptoms and is usually recommended over quitting “cold turkey.” However, tapering off the drug takes longer. Due to the risk of methadone misuse and overdose, methadone therapy is only available to people who are enrolled in a government-approved treatment program. A doctor monitors your methadone intake and response to make sure that the withdrawal process is safe and effective.

What is Methadone Withdrawal

Weeks 3-4 — Post-Acute Withdrawal Symptoms (PAWS)

What is Methadone Withdrawal

A person should make sure that they are under medical supervision throughout the entire process. After methadone withdrawal https://prolificvent.com/the-role-of-detox-centres-in-addiction-treatment/ symptoms peak between days three and eight, it can take around 10 days for withdrawal symptoms to subside. In some cases, it may take longer for withdrawal to resolve completely. Symptoms of withdrawal from methadone are similar to those of other opiates, such as heroin and morphine.

Duration Of Withdrawal

What is Methadone Withdrawal

Prisoners in New South Wales, Australia, can access methadone and buprenorphine maintenance treatment. Continuity of maintenance treatment between prison and community settings is critical to reducing the risk of relapse to drug use and criminal re-offending. It is recommended that all patients receiving MMT in closed settings be assisted to transfer to a community-based MMT program to continue treatment.

Certain symptoms during methadone withdrawal require immediate medical evaluation. Recognizing these warning signs could prevent serious complications or save your life. Medication-assisted treatment continues playing a crucial role even after methadone withdrawal. Many individuals transition to other MAT options like buprenorphine or naltrexone to maintain long-term recovery stability. Opioid use disorder is a complex, treatable chronic medical condition from which people can recover. Other medications may interact with methadone and cause heart conditions.

Treatment with methadone or buprenorphine is recommended for pregnant women with opioid use disorder. Buprenorphine treatment may lead to better health outcomes for infants than methadone treatment. Certified treatment programs are obligated to prescribe and dispense methadone in accordance with the treatment requirements outlined in the Federal Opioid Treatment Standards (42 CFR 8.12). Addiction to opioids, such as heroin and prescription opioids, is the leading cause of drug overdose in the United States. For those with addiction, untreated physical and psychological withdrawal symptoms may be severe, making it challenging to abstain from using the drug.

It’s possible for some people to become addicted to methadone as they use it to wean themselves off of another prescription painkiller. A distressing withdrawal from methadone is likely to lead to relapse. Patients tend to be successful when the taper is slow and they are surrounded by support.

Typically administered as a “maintenance dose,” methadone can suppress withdrawal symptoms for 24 to 36 hours. While it plays a vital role in saving lives by preventing overdose deaths, one significant downside is its Sobriety potential to cause extended withdrawal symptoms when discontinued. Doses should be decreased for reports of symptoms of opioid intoxication or oversedation.

Prodia the CRO awarded as 2023 Indonesia CRO Company of the Year

Posted on December 9, 2024May 20, 2025 by admin

As a leading CRO company in Indonesia, Prodia the CRO keeps on taking steps forward and strives to be in our best potential. Being the award-winner of this category for 2 years in a row increases our confidence as well as our eagerness to improve our services, to adapt more and dive deeper into this industry and give better support to our customers and partners.

Referring to Frost & Sullivan’s report, Asia-Pacific’s (APAC) contract research organization (CRO) space has matured since the COVID-19 pandemic. The region’s significance in the industry is due to a notable increase in clinical research activities, particularly during the pandemic. Thanks to evolving trial dynamics, countries like Indonesia increasingly draw drug sponsors and CROs with well-developed infrastructure and diverse demographics. Prodia the CRO with our expertise and established networking across the country, and through our local-wise understanding about the clinical trial environment, always try to ensure that the desired goal of the clinical trials which is to obtain the best research outcome in the most effective way, efficient cost and timeline, without neglecting the rights of the patients and ethical aspects of the procedures, could be reached by great trial management throughout project preparation and conduct.

This recognition is the result of many individuals: hard work of our employees, and ultimately, the trust of our customers, partners, and investors who make critical decisions every day to support Prodia the CRO and contribute to our future. Thank you for believing in Prodia the CRO.

FROST & SULLIVAN 2022

Posted on December 9, 2024December 12, 2024 by admin

Prodia the CRO earns Frost & Sullivan’s 2022 Indonesia Company of the Year Award in the contract research organization industry. (Check out the video)

FROST & SULLIVAN 2021

Posted on December 9, 2024December 12, 2024 by admin

In 2021, Frost & Sullivan recognizes Prodia’s commitment towards building a one-stop destination for all CRO client needs within and beyond Indonesia. Frost & Sullivan commends Prodia for successfully identifying industry challenges and directly tackling them. With its strong overall performance, PT. Prodia Diacro earns Frost & Sullivan’s 2021 Indonesia Customer Value Leadership Award in the contract research organization industry. (readmore)

FROST & SULLIVAN 2020

Posted on December 9, 2024 by admin

Frost & Sullivan announced PT. Prodia Diacro Laboratories as the recipient of the 2020 Indonesia CRO Customer Value Leadership Award. The Frost & Sullivan Best Practices awards have identified and honored best-in-class companies that have demonstrated excellence in their respective industries. Award recipients were identified based on indepth interviews, analysis, and extensive secondary research conducted by Frost & Sullivan’s analysts.

Watch the Video of the 2020 Frost & Sullivan Asia-Pacific Best Practices Virtual Awards Ceremony.

Top 10 Clinical Trial Management Consulting/Service Companies in APAC – 2020

Posted on December 9, 2024 by admin

Clinical research and trials are an important part of pharmaceutical R&D. They not only ensure quicker ROI made for the pharma firm but also drive better and safer access to patient care.

Every clinical research and trial initiative is held on achieving two core believes-reach new market segments and introduce new drugs. Numerous pharma firms are taking steps toward incorporating the latest techniques to attain these targets. One of the ways to realize such activity is by outsourcing clinical research practice. A trend resulting from high drug costs-outsourcing of clinical research-is reshaping the drug development services industry. Today, enterprises in pharma clinical research offer services ranging from preclinical evaluations, study design, and clinical trial planning and management to independent safety data monitoring and bio-statistical analysis. Even adopting electronic records has seen a surge in the last few years. Clinical research service providers are going paperless to ensure that their operations around drug applications such as researching, analysis, and data management are manual-free, error-free, swift, easy, and automatic. These electronic records have also found support from the latest technologies that capture the clinical trial management systems for administrative information.

The integration of silos of pharma and clinical research- related information flowing through numerous networks from one medical firm to another is yet another challenge that needs to be eliminated through clinical development and commercialization. In the near future, the upcoming trend is likely to relate to integrating the data collection, data management, data repository, and safety data under one centralized platform.

In this edition, Pharma Tech Outlook has compiled a list of Top 10 Clinical Trial Management Consulting/Service Companies in APAC 2020 that are offering services that improve the clinical research and trial for every pharma firm. Simultaneously, Pharma Tech Outlook also explores the untapped opportunities that might otherwise go unseen by many service providers and pharma firms in the clinical research and trial space.

We present to you Pharma Tech Outlook’s “Top 10 Clinical Trial Management Consulting/Service Companies in APAC – 2020”

Prodia the CRO Revolutionizing the Clinical Studies

Prodia the CRO was established in 2007 as a fullservice CRO with the focus on delivering good clinical practices (GCP-based) trial support to healthcare firms in Indonesia. Headquartered in Jakarta, Prodia brings togetherthe ethically-diverse Indonesian manuscript writing, study conduct, and training on protocol development to its customers and partners. Through the collaborations with Prodia the CRO, many internationally acclaimed CROs receive unparalleled service that includes conducting a feasibility study for their potential population with the nation’s fast growing medical infrastructure projects and consultation on medical devices. “We act as a and lower trial costs to develop an integrated service suite. The company’s solution portfolio includes site management, study document development, clinical trial consulting, clinical trial submission, clinical study monitoring, medical writing, and quality assurance and audit. “Our ultimate mission is to provide GCP trials with competitive cost, timeline-bound delivery, and compliance with ICH-GCP guidelines to biopharmaceutical and biotechnology companies and other global CROs,” states Erizal Sugiono, Director of Prodia the CRO. “Our accumulative and vast experiences in providing clinical trial services to local as well as multinational companies with a commitment to reach quality through qualified and dedicated resources helps us stay ahead of the curve in the Indonesian market.”

One of the major challenges in clinical trial development and study is around locating, selecting, and assessing a site/location that can adequately support healthcare organizations in conducting unbiased clinical trials. Many leading biopharmaceutical companies and global CROs are repetitively demanding for a reliable partner that could assist them through the site monitoring process, either on-site or remotely. Prodia addresses this issue by performing site capacity building to find a location that supports clinical research units (CRU) and is equipped with good systems, resources, and infrastructure. To discover such a site for its clients, Prodia the CRO has formulated a site management organization (SMO) division that empowers sponsors and investigators to administer the CRUs with various services—feasibility study,

provision of site staff, training, and subject recruitment. “Our SMO is developed to collaborate with other CROs and medical organizations to increase the number of qualified clinical trial sites all across Indonesia,” mentions Erizal. The company also places significant focus on imparting GCP training along with manuscript writing, study conduct, and training on protocol development to its customers and partners. Through the collaborations with Prodia the CRO, many internationally acclaimed CROs receive unparalleled service that includes conducting a feasibility study for their potential projects and consultation on medical devices. “We act as a rescue CRO for some local studies in Indonesia. Once a medical organization has established a potential study in Indonesia, their preference of local CRO to work with is Prodia, without a second thought,” exclaims Rosalia.

Prodia the CRO also has a sister company, Prodia Laboratory that provides a highly-advanced and equipped laboratory space for clinical trial testing. Currently, Prodia Laboratory expanded its capability to offer Next Generation Sequencing (NGS) testing and genomic testing for early detection of cancer risk, nutrigenomics tests, and metabolomic tests. Besides, to fulfill the clients’ demands around biological product clinical trial, Prodia Laboratory serves the anti-drug antibodies (ADA) testing.

The future holds immense possibilities for Prodia the CRO. The company has mapped out a dynamic growth plan that includes expanding its business scope to incorporate clinical safety and efficacy testing of cosmetic products. The testing will play a key role in substantiating product claims whilst also ensuring that the products are safe and effective for consumer use. “Our cosmetics clinical testing service is designed to support the client from study design and planning to reporting stage. Overcoming challenges in carrying out clinical trials, such as volunteer recruitment and ensuring that clinical data is robust, is essential for success,” mentions Erizal. To further achieve its objective in clinical trial management, Prodia the CRO is pursuing the advance technology for laboratory testing along with Prodia Laboratory and planning on extending to provide e-CTMS/ CRF. “Our mission is to lead the Indonesian clinical trials management market and with such a plan of action, we are on the track to achieve that goal,” concludes Erizal.